Potentiation of antigen‐specific, Th1 immune responses by multiple DNA vaccination with an ovalbumin/interferon‐γ hybrid construct
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چکیده
منابع مشابه
Th1 Platform Immune Responses Against Leishmania major Induced by Thiol-Specific Antioxidant-Based DNA Vaccines
BACKGROUND The Thiol-specific antioxidant (TSA) is an antigen of Leishmania major which is believed to be the most promising molecule as a vaccine candidate against leishmaniasis. OBJECTIVES In this study, we investigated the protective efficacy of TSA-based DNA vaccine against L. major infection. MATERIALS AND METHODS Recombinant plasmid construction TSA (pcTSA) was prepared and transfecte...
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ژورنال
عنوان ژورنال: Immunology
سال: 1998
ISSN: 0019-2805,1365-2567
DOI: 10.1046/j.1365-2567.1998.00510.x